Cerebral oxygenation in highlanders with and without high-altitude pulmonary hypertension

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منابع مشابه

High-altitude pulmonary oedema in native highlanders.

To cite: Yanamandra U, Patyal S, Mukherji R, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-202513 DESCRIPTION A 28-year-old Ladakhi police personnel, native highlander, serving at high altitude (∼12 000 ft) presented with a short history of cough and breathlessness while on leave for 10 days at the same altitude. There was no history of deinduction ...

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High-altitude pulmonary hypertension.

High-altitude pulmonary hypertension (HAPH) is a specific disease affecting populations that live at high elevations. The prevalence of HAPH among those residing at high altitudes needs to be further defined. Whereas reduction in nitric oxide production may be one mechanism for the development of HAPH, the roles of endothelin-1 and prostaglandin I₂ pathways in the pathogenesis of HAPH deserve f...

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PULMONARY HYPERTENSION Phosphodiesterase type 5 and high altitude pulmonary hypertension

Background: This study explored phosphodiesterase type 5 (PDE5) inhibition as a strategy for treating high altitude pulmonary arterial hypertension (HAPH). Methods: 689 subjects (313 men) of mean (SD) age 44 (0.6) years living above 2500 m were screened for HAPH by medical examination and electrocardiography, and 188 (27%) met the criteria for right ventricular hypertrophy. 44 underwent cardiac...

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High-altitude pulmonary edema in children with underlying cardiopulmonary disorders and pulmonary hypertension living at altitude.

BACKGROUND Pulmonary hypertension has not been described as a predisposing risk factor for high-altitude pulmonary edema (HAPE) in children. Previous studies have shown an association of HAPE with abnormally increased pulmonary vasoreactivity to hypoxia but generally normal pulmonary artery pressure (PAP) after recovery. OBJECTIVE To describe HAPE of relatively rapid onset and its management ...

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Compromised Cerebrovascular Regulation and Cerebral Oxygenation in Pulmonary Arterial Hypertension

BACKGROUND Functional cerebrovascular regulatory mechanisms are important for maintaining constant cerebral blood flow and oxygen supply in heathy individuals and are altered in heart failure. We aim to examine whether pulmonary arterial hypertension (PAH) is associated with abnormal cerebrovascular regulation and lower cerebral oxygenation and their physiological and clinical consequences. M...

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ژورنال

عنوان ژورنال: Experimental Physiology

سال: 2015

ISSN: 0958-0670

DOI: 10.1113/ep085200